报告题目 |
Conjugated Polyelectrolyte as a New Platform for Biological Sensing and Imaging |
报告时间 |
2009年10月22日 下午 16:00 |
报告地点 |
合肥微尺度物质科学国家实验室,18层大楼一层报告厅 |
报告摘要 |
There is an increasing trend of using light-harvesting conjugated polyelectrolytes as signal reporters or signal amplifiers for chemical and biological detection. Cationic conjugated polyelectrolytes (CCP) in conjunction with dye labeled peptide nucleic acid probes have been used for sequence specific DNA detection with high sensitivity and selectivity. The signal output is largely dependent on the signal amplification provided by the CCP, which is greatly affected by the energy transfer efficiency between the CCP and the dye. In this talk, we will discuss different strategies to improve the fluorescent signal output and detection sensitivity for several DNA and protein assays. In addition, our recent progress of using CCPs for real-time naked eye detection and quantification of chemical and biological molecules will also be discussed. |
报告人 |
Prof. Bin Liu |
报告人简介: | |
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