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报告题目 |
Building molecules for biological imaging applications |
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报告时间 |
2011年5月6日(星期五)上午10:00 |
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报告地点 |
微尺度国家实验室一楼科技展厅 |
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报告摘要 |
Non-invasive molecular imaging opens a window into the biology of living subject, and its success is critically dependent on the development of chemical probes to enable direct visualization of specific molecular targets and processes. This talk will highlight some of our efforts in building these molecules. The first example involves the design and synthesis of fluorogenic substrates for imaging the activity of bacterial enzyme beta-lactamase in mice to facilitate the detection and study of tuberculosis, one of the most frequent causes of death worldwide. In the second example, I will discuss the concept of developing biocompatible chemical reactions to synthesize nanostructures in cells and demonstrate its application for imaging of protease activity. These examples aim to underline the important role of chemistry in this rapidly evolving field of molecular imaging. |
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报告人 |
Prof. Jianghong Rao, Stanford University School of Medicine, USA |
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报告人简介：⑴、现在工作单位及职称 ⑵、主要研究方向 ⑶、学术成就简述（100字以内） Prof. Jiangjong Rao is an Assistant Professor of Radiology Department of Stanford University. Current research interests of his lab include enzyme-activity based in vivo imaging, in vivo protein and RNA labeling, and new sensing and imaging technologies. He received numerous prestigious awards such as Burroughs Wellcome Career Award at the Scientific Research Interfaces and Human Frontier Science Program Young Investigator Award. He has more than 50 published papers on top journals including Science, Nature Biotechnology, Nature Chemistry, PNAS, JACS, Angewandte Chemie, et al. | |
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接待单位联系人：梁高林 电话：18715161913 | |
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主办单位： 化学与材料科学学院 学院， 外办（港澳台办） | |