报告题目 | Practical Catalytic Hydrogenation |
报告时间 | 2013年10月8日（周二）下午15:00 |
报告地点 | 东区环境与资源楼（新化学楼）学术报告厅 |
报告人 | 张绪穆 教授武汉大学化学与分子科学学院 |
报告摘要 | Dr. William Knowles, in his 2001 Nobel Lecture, described his 1960s and 70s work in developing asymmetric hydrogenation catalysts. Now, almost 40 years later, although major advances have been made (e.g. Professor Noyori’s Nobel prize winning work in asymmetric hydrogenation), significant challenges still remain. On the one hand, this presentation describes innovation in asymmetric hydrogenation catalysis from both an academic and industrial perspective. It highlights recent advances and the commercialization processes regarding asymmetric hydrogenation. The broad array of asymmetric hydrogenation catalysts and their numerous applications for a variety of functional group hydrogenations will be reviewed. We will emphasis on the practical applications of asymmetric hydrogenation to make chiral pharmaceuticals and address unmet needs in asymmetric hydrogenation. The knowledge gained in this research can lead to “next generation” catalysts. The versatile P-Chiral ligandsdeveloped by Zhang group S. Li, K. Huang, B. Cao, J. Zhang, W. Wu, X. Zhang. Angew. Chem. Int. Ed. 2012, 51, 8573-8576. K. Huang, S. Li, M. Chang, X. Zhang. Org. Lett. 2013, 15, 484-487. T. Liu, C. Wang, X. Zhang. Angew. Chem. Int. Ed. 2013, 52, 8416-8419. |
报告人 简介 | 2011- present: Professor , Wuhan University, China 2007-present: Distinguished Professor, Rutgers, The State University of New Jersey, NJ, USA 2003-2007: Professor, The Pennsylvania State University, University Park, PA,USA 1999-2003: Associate Professor, The Pennsylvania State University, University Park, PA, USA 1994-1999: Assistant Professor, The Pennsylvania State University, University Park, PA, USA 1992-1994: Postdoctoral, Stanford University, Stanford, CA, USA 1987 - 1992: Ph. D., Stanford University, Stanford, CA, USA 1985 - 1987: M.S., University of California, San Diego, CA, USA 1982 - 1985: M.S., Physical and Inorganic Chemistry, Chinese Science Academy 1978 - 1982: B.S., Wuhan University |
参加者：所有感兴趣的老师和学生 | |
化学与材料科学学院，中国科学技术大学研究生院 | |