11月28日研究生学术前沿讲座——Prof. Masahiro Terada

报告题目

Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Transformations

报告时间

2011年11月28日上午10：00点

报告地点

微尺度国家实验室一楼科技展厅

报告人

Prof. Masahiro Terada

Department of Chemistry

Tohoku University, Japan

报告摘要:

The electrophilic activation of a substrate by means of a Brønsted acid is the most straightforward and common approach used to promote a reaction and hence Brønsted acids have been widely utilized as efficient catalysts for numerous organic transformations. The development of novel Brønsted acid catalysts has been continuously studied due to their broad synthetic applicability. In the past decade, innovative research on Brønsted acid catalysis has enabled great progress. Specifically, research has focused on ‘chiral Brønsted acid catalysis’, in which enantioenriched products are obtained using a catalytic amount of a chiral organic molecule bearing an acidic functionality. Currently, chiral Brønsted acids represent a widely applicable class of catalysts for a variety of enantioselective transformations. In this lecture, I would like to introduce the recent achievements in developing enantioselective carbon-carbon bond forming reactions using 1,1’-bi-2-naphthol (BINOL)-derived phosphoric acids as chiral Brønsted acid catalysts. 

报告人简介：

Masahiro Terada graduated from Department of Applied Chemistry, Tokyo Institute of Technology in 1986 and received his PhD in 1993 from Tokyo Institute of Technology. He was appointed as an Assistant Professor in Professor Mikami’s Laboratory at Tokyo Institute of Technology (1989). He worked as a postdoctoral fellow with Professor M. D. Shair at Harvard University in 1999-2000 and moved to Tohoku University as an Associate Professor in 2001. He has been a Professor of Chemistry at the Graduate School of Science, Tohoku University (Japan) since 2006. Now he has published more than 150 papers (including review articles) and 16 patents. He is the recipient of the Incentive Award in Synthetic Organic Chemistry, Japan (2003), The Chemical Society of Japan Award for Creative Work (2008), and Mukaiyama Award (2010). ACP Lectureship Award 2010 form China and Hong Kong. He is now a Head Investigator of Scientific Research on Innovative Areas “Advanced Molecular Transformations by Organocatalysts”, supported by Grant-in-Aid for Scientific Research from The MEXT, Japan (FY 2011-2015). His current research interests are focused on the development of new and useful synthetic methodologies based on the design of novel chiral Brønsted acid and base catalysts as well as the utilization of transition metal catalysts.

主办单位：微尺度国家实验室，化学与材料科学学院，研究生院