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报告题目 |
Lighting Up Diseases with Dark Materials |
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报告时间 |
2014年10月28日(星期二)上午10:00 |
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报告地点 |
环境资源楼报告厅 |
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报告摘要 |
A variety of molecular platforms including small molecules, peptides, aptamers and nanoparticles have been explored for molecular imaging of diseases. Melanin is a natural dark pigment that can be found in most organisms. In malignant melanoma, melanin formation is highly increased because tyrosinase activity is significantly elevated. Therefore it can serve as a promising molecular target for melanotic melanoma imaging. Imaging probes that either are involved in the melanin biosynthesis pathway or have high affinities with melanin could be developed for melanin targeted imaging. In this lecture, we will present our research on developing benzamide analogs for melanin targeted molecular imaging. More interestingly, melanin can also serve as a target for multimodality imaging of diseases including PET, MRI and photoacoustic imaging (PAI). Our recent research efforts on this direction will be presented in this talk as well. |
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报告人 |
Prof. Zhen Cheng, Stanford University School of Medicine, USA |
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报告人简介：⑴、现在工作单位及职称 ⑵、主要研究方向 ⑶、学术成就简述（100字以内） Dr. Zhen Cheng is an Associate Professor of Radiology and a member of the Molecular Imaging Program at Stanford (MIPS), BioX program, Canary Center at Stanford for Cancer Early Detection and Stanford Cancer Center. He currently is the Director of the Cancer Molecular Imaging Chemistry Laboratory where he is developing novel molecular probes especially PET, SPECT, optical and photoacoustic probes, non-invasive imaging techniques, and bionanotechnology for the multimodality early detection of diseases including cancer, cardiac and neurological diseases. Dr. Cheng has published over 150 peer reviewed articles, 6 book chapters, and he is a co-inventor of 14 patents. Dr. Cheng is the President-elect and Chair of Board of Directors, Chinese American Society of Nuclear Medicine and Molecular Imaging, and he was the Board Director of the Radiopharmaceutical Sciences Council in the Society of Nuclear Medicine and Molecular Imaging. He has served as a reviewer for numerous funding agencies including NIH, DOD, DOE, German Research Foundation, National Natural Science Foundation of China, etc. He has also served as an active reviewer for over 100 research journals such as Nature Nanotechnology, Nature Communications, Science Translational Medicine, JACS, Angewandte Chemie, JNM, etc., abstract reviewer and session chair for numerous meetings (SNM, WMIC, etc.). Moreover, he is Associate Editor of Frontiers in Biomedical Physics and Regional Editor ofCurrent Molecular Imaging and sits on the editorial board of numerous peer-reviewed journals. | |
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主办单位： 化学与材料科学学院， 外办（港澳台办） | |